A case of 66yearold south indian post menopausal woman presenting a giant ovarian serous cyst adenoma weighing 23 kg is reported here. This type of cystadenoma can grow really large and may appear to be solid at first sight. Typically, a serous cystadenoma is morphologically classified as having either a polycystic, honeycomb, or oligocystic pattern. Mar 16, 2020 if such foci represent 10% of the tumor volume, the tumor is designated serous cystadenoma with focal epithelial proliferation.
Resection is generally carried out for symptoms, large size, or the inability to distinguish a serous cystic neoplasm from a mucinous lesion, which has greater. These tumors consist predominantly of small cysts microcystic adenomas. Ct of serous cystadenoma of the pancreas and mimicking masses. This serous cystadenoma was composed of a smoothwalled unilocular cyst except for one focus shown here with papillary architecture. Rare presentation of serous cystadenoma as hemorrhagic cyst author. Serous cystic neoplasms of the pancreas are rare in children and adults, are more often observed in females, and are found mainly in the body and tail of the pancreas. Further growth of oei forms serous cystadenoma, serous borderline tumor, and lgsc in a stepwise fashion. Pdf ovarian serous cystadenoma associated with sertoli. Ovarian serous cystadenoma radiology reference article. Ovarian serous cystadenoma primarily occurs unilaterally 5, 6. They occur in adults of all ages, with reported mean ages differing from 40 to 60 years.
Benign serous cystadenoma, ovarian tumor, papillary projections, peritoneal carcinomatosis, mr imaging. Apr 06, 2017 cystic neoplasms of the pancreas are less common, accounting for about 1015% of all cystic pancreatic lesions. Full text discrimination of serous cystadenoma from. A benign cystic tumor of the ovary, made up of cylindrical cells resembling those of the uterine tube. Ovarian serous cystadenoma, on the basis of the amount of fibrous tissue, can be classified into 6 types. Ovarian serous cystadenoma and treatment answers on. Ovarian serous cystadenoma, also less precisely known as serous cystadenoma, is the most common ovarian neoplasm, representing 20% of ovarian neoplasms, and is benign it has a very superficial resemblance to the most common type of ovarian cancer serous carcinoma of the ovary under the microscope. The symptoms and signs are nonspecific and most commonly include pelvic pain, discomfort, or an asymptomatic pelvic mass discovered on routine examination. They are the commonest type of ovarian epithelial neoplasm. What is the most appropriate and least invasive primary therapy for a 4cm serous pancreatic cystadenoma that is clearly connected to side branches of the main pancreatic duct.
They are most likely to appear towards the end of a womans reproductive life or after it, specifically between the ages of 40 and 50. Resected serous cystic neoplasms of the pancreas jefferson. Serous cystadenoma is a benign pancreatic cystic neoplasm. Serous cystadenoma is a tumor in the ancient use of the term when it referred simply to a mass. The two most common cystic neoplasms of the pancreas are serous cystadenoma and mucinous cystic neoplasms. Benign ovarian cysts are one of the most common gynecological conditions occurring in the adolescent and reproductive age group. Cystadenoma definition by definition, this is a benign tumor of glandular origin that has one or more cavities lined with the tumor cells and containing some type of fluid. Pdf ovarian huge serous cystadenoma in adolescent girl. We describe a patient, whose pancreatic cyst exhibited a radiological appearance distinct from that of typical serous cystadenoma, resulting in diagnostic difficulties. Jan, 2019 what is the prognosis of serous cystadenoma of pancreas.
Fertility sparing surgery for management of serous cystadenoma. In medicine such transparent, clear liquid called serosal, hence the name of the tumor. Benign ovarian serous cystadenoma mimicking papillary thyroid. Pathology outlines who classification of ovarian neoplasms. Atypical manifestations of serous cystadenoma can include giant tumors with ductal dilatation, intratumoral hemorrhages, solid variants, unilocular cystic tumors, interval growth, and a disseminated form.
Ovarian huge serous cystadenoma in adolescent girl. Papillary tumors have papillary projections on outer surface or protruding into cystic cavity cystadenoma. The serous cystadenoma is an interesting lesion of the ovary 4. After a successful surgery, the ovarian cyst, measuring 40 centimeters and weighing 8 kilograms, was removed. Mar 16, 2017 serous papillary cystadenoma of ovary is a slow growing tumor and it more often than not manifests as a well defined, painless single mass in the ovary. Ovarian serous neoplasms are the commonest of four general types of the epithelial ovarian tumors, and are more prevalent than the mucinous ovarian tumors serous ovarian neoplasms are subdivided into benign, borderline, and malignant lesions according to their malignant potential and clinical behavior see pathology classification section below. Response and survival in patients with progressive or recurrent serous ovarian tumors of low malignant potential. The remaining 157 patients were initially diagnosed with benign serous cystadenoma. Both are multiloculated cystic neoplasms and are lined by a single layer of tall columnar cells with a clear basal nucleus and cytoplasm. Serous cystadenofibroma and adenofibroma of the ovary can be considered variants, and are also dealt with in this article. Jul 23, 2009 giant ovarian serous cyst adenoma of such a huge size is a rare finding. Morphologically similar tumors were classified as serous cystadenoma if the proliferative area involved less than 10% of the tumor. Giant ovarian serous cystadenoma in a postmenopausal woman.
Prmc and benign mucinous cystadenoma of the ovary are microscopically similar. Serous ovarian tumors are traditionally described with a cyst prefix because of their primarily cystic composition, e. These criteria are in accordance with the recent nci. Mar 16, 2020 webpathology is a free educational resource with 10274 high quality pathology images of benign and malignant neoplasms and related entities. Ovarian serous cystaden oma, also less precisely kno wn as serous cyst adenoma, is the mo st common ovarian neoplasm, represen ting 20% of ovarian neoplasms, and is benign it has a very superficial resemblance to the most c ommon type of o varian cancer serous carcinoma of the ovary under the microscope. Outcomesresolutions the prognosis of serous cystadenoma of pancreas is excellent with appropriate treatment. The most remarkable descriptions of large ovarian cysts are those of spohn, who in 1922 reported one that weighed 148. Pancreatic serous cystadenoma with compression of the main. Since at present the term tumor is equated with neoplasm, we believe that serous cystadenoma no longer qualifies for this designation. Between 1223% of cystadenomas are involve both ovaries. Serous cystadenoma article about serous cystadenoma by the. The cyst is usually unilocular, but it can be multilocular. Discrimination of serous cystadenoma from mucinous cystadenoma in the pancreas with contrastenhanced ultrasonography. Even though mucinous cystadenoma are common ovarian tumor, what makes prmc so rare is their retroperitoneal location.
Serous cystadenoma simple and papillary serous cystadenoma ovary is the most popular among all ovarian cysts 70%. Pathology outlines serous cystadenoma adenofibroma. Abstract a case of 15 yearoldgirl with the ovarian papillary cystadenoma with borderline lesion was presented with special reference to the comparison between histology of the tumor and cytology of the cyst fluid incidentally obtained by peritoneal jstage. Serous cystadenoma of the pancreas pubmed central pmc. In all, 106 patients diagnosed with serous cystadenoma were identified. Serous cystadenomas account for 60% of ovarian serous tumors 1. Anterior and posterior wholebody planar images from a thyrogenstimulated diagnostic i1 scan at 52 hours show a. The purpose of this article is to illustrate the varied ct appearances of serous cystadenoma of the pancreas and of masses that mimic serous cystadenoma. Typical and atypical manifestations of serous cystadenoma of.
Most of the signs and symptoms recede and disappear on removal of the tumor. The world health organization histological classification for ovarian tumors separates ovarian neoplasms according to the most probable tissue of origin. This is a common benign ovarian tumor diagnosed by microscopic examination. Usually 310 cm, oval to round, smooth glistening surface.
While serous cystadenoma is the most common of them all, they rarely grow to large sizes unless. Causes of ovarian serous cystadenoma answers on healthtap. We present this case because collision tumors in ovary are a rare entity and combination of serous cystadenoma with teratoma is rarer 1. Ruptured benign serous ovarian cystadenoma mimicking ovarian. The term serous cystadenoma has been in use for at least a century. Pancreatic serous cystadenoma is a benign tumour of pancreas. Ovarian lowgrade serous carcinoma lgsc development starts from tubal epithelia, which invaginate into ovarian stroma to form ovarian epithelial inclusions oei. With prompt and appropriate treatment, the prognosis is generally excellent. Serous cystadenoma is more common than mucinous cystic neoplasm, with a ratio of about 2. Pdf ovarian cysts are an extremely common gynecological problem in adolescent. Ovarian serous cystadenomas are a type of benign ovarian epithelial tumor at the benign end of the spectrum of ovarian serous tumors. Serous cystadenoma is a benign neoplasm that is usually present either in ovaries or in pancreas.
Aug 06, 2018 the treatment for benign serous cystadenofibroma of ovary is complete surgical removal of the tumor. Cea levels over 800 ngml strongly suggested mucinous cystadenoma or mucinous cystadenocarcinoma sensitivity 48%, specificity 98%. It has been viewed from such angles as hugeness in not only an adolescent girl 5 and a young woman 6 but also in a. They can occur nearly anywhere and are very familiar in the ovaries. Since serous cystadenomas are benign, unilateral salpingooophorectomy or ovarian cystectomy is adequate treatment. Pancreas, serous cystadenoma, computed tomography, pancreatic cysts. The study concluded that the pooled analysis of individual patients showed that. Though collision tumors have been reported earlier, combined serous cystadenoma with mature cystic teratoma is rarely reported. Mismanagement of a huge ovarian serous cystadenoma in a.
Serous cystadenomas constitute about 40% of all ovarian tumours occurring in the reproductive age group. Benign serous tumors of the ovary represent 16% of all ovarian epithelial neoplasms and account for twothirds of benign ovarian epithelial tumors and the majority of serous ovarian tumors. In contrast to some of the other cystforming tumors of the pancreas such as the intraductal papillary mucinous neoplasm and the mucinous cystic neoplasm, serous cystic neoplasms are almost always entirely benign. The common cystic neoplasms considered to be benign include serous cystadenoma and pseudocysts, whereas mucinous cystadenoma and. They are usually cystic, either unilocular or multilocular, and the cysts contain clear fluid. Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more. Between 15 and 25 percent of serous cystadenomas are bilateral, meaning they will appear on both ovaries. The full text of this article is available in pdf format. However, regular follow up visits with the healthcare provider are important. Some of the papillae had simple architecture with no secondary branching. Rare presentation of serous cystadenoma as hemorrhagic cyst. About 1525% occur bilaterally and about 2025% are malignant. Mar 14, 2011 serous cystadenoma is a common benign neoplasm that can be managed without surgery in asymptomatic patients provided that the diagnosis is certain. Ovarian serous cystadenoma associated with sertolileydig cell tumor a case report article pdf available in journal of korean medical science 111.
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